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Abstract Objective To explore the relationship between lumbar psoas muscle index (PMI),lumbar vertebral bone marrow fat fraction (FF) and bone mineral density (BMD) and the diagnostic efficacy of osteoporosis (OP).Methods 200 cases of BMD exam in our hospital from March 2018 to May 2021 were selected as the research objects.According to BMD,they were divided into normal bone mass group (T value≥-1.0,n=105) and bone mass reduction group (-2.5<T value <-1.0,n=57),OP group (T value ≤-2.5,n=38).General information and BMD,PMI,lumbar vertebral bone marrow FF were compared in 3 groups.The relationship between PMI,lumbar vertebral bone marrow FF and BMD were analyzed.OP’s Logistic regression model was established.The diagnostic efficacy of PMI and lumbar vertebral bone marrow FF for OP was evaluated.Results The BMD and PMI of the OP group were lower than those of the osteopenia group and the normal bone mass group,and the FF was higher than that of the osteopenia group and the normal bone mass group (P<0.05).The BMD and PMI of the osteopenia group were lower than those of the normal bone mass group,and the FF was higher than that of the normal bone mass group (P<0.05).PMI was positively correlated with BMD,and lumbar vertebral bone marrow FF was negatively correlated with BMD (P<0.05).Age,body mass index,PMI,lumbar vertebral bone marrow FF were the influencing factors of bone loss,and age,PMI,lumbar vertebral bone marrow FF were the influencing factors of OP (P<0.05).The AUC of the combined diagnosis of OP with lumbar vertebral bone marrow FF was 0.853,and it was greater than the single index diagnostic value (P<0.05).Conclusion PMI and lumbar vertebral bone marrow FF are independent influencing factors of BMD,and the combination of the two has a high efficiency in the diagnosis of OP.
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Corresponding Authors:
Zhang Wenju
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