|
|
|
Abstract Objective To evaluate the radiological features and clinical findings in osteoporotic patients with degenerative lumbar scoliosis (DLS).Methods From November 2017 to December 2021，27 DLS patients combined with osteoporosis (OP) were enrolled as OP group.The OP group had 5 male and 22 femaile patients and had an average age of (68.1±7.4) years (51~79 years).At the same time，another 27 DLS patients without osteoporosis were recruited as the nonosteoporosis (NOP) group.The NOP group had 8 males and 19 females and had an average age of (66.3±6.9) years (53~76 years).Bone mineral density (T-score) and clinical symptoms were recorded.The radiographic parameters were measured in standing full spine X-ray film and further compared between two groups.The correlation between the T-score and radiographic parameters was analyzed in the OP group.Results The median T-score in the OP group (－3.0±0.6) was significantly lower than that in the NOP group (－0.6±1.4).The percentage of back pain，motor deficit and sensory deficit were comparable between two groups (P＞0.05).There were 13 left lumbar curves and 14 right lumbar curves in the OP group.There were 11 left lumbar curves and 16 right lumbar curves in the NOP group.No significant differences were observed in terms of radiographic parameters including lumbar and thoracic cobb angle，apical vertebral translation，apical vertebral rotation，thoracic kyphosis，lumbar lordosis，coronal and sagittal trunk shift (P＞0.05).A significant correlation was found between Tscore and thoracic kyphosis in OP group (r＝－0.568，P＝0.022).Conclusion The coronal and sagittal profile are comparable between DLS patients with and without osteoporosis.The severity of osteoporosis is obviously correlated with thoracic kyphosis in osteoporotic patients.
|
|
|
| Fund:无锡市卫生健康委科研基金资助项目(Q202060) |
|
Corresponding Authors:
Wang Qiang
|
|
|
|
［1］胡巍然，施新革，王红强，等.退变性脊柱侧凸术后脊柱骨盆参数特点及生活质量相关性分析［J］.实用骨科杂志，2020，26(6)：481-486.
［2］Shi B，Liu D，Zhu Z，et al.Sequential correction technique in degenerative scoliosis with type C coronal imbalance：A comparison with traditional 2-rod technique［J］.J Neurosurg Spine，2021(24)：1-7.
［3］王小阵，鲁齐林，吕鹏，等.骨水泥强化椎弓根螺钉内固定术治疗骨质疏松性腰椎滑脱症［J］.实用骨科杂志，2021，27(4)：354-358.
［4］Siris ES，Adler R，Bilezikian J，et al.The clinical diagnosis of osteoporosis：A position statement from the national bone health alliance working group［J］.Osteoporos Int，2014，25(5)：1439-1443.
［5］邱勇，王斌，朱锋，等.退变性腰椎侧凸的冠状面失衡分型及对截骨矫形术式选择的意义［J］.中华骨科杂志，2009，29(5)：418-423.
［6］鲍虹达，朱锋，邱勇，等.退变性脊柱侧凸患者后路矫形术后腰椎前凸指数对矢状面平衡的预测作用［J］.中国脊柱脊髓杂志，2016，26(4)：289-293.
［7］Yamada K，Nakamae T，Nakanishi K，et al.Long-term outcome of targeted therapy for low back pain in elderly degenerative lumbar scoliosis［J］.Eur Spine J，2021，30(7)：2020-2032.
［8］Zou D，Jiang S，Zhou S，et al.Prevalence of osteoporosis in patients undergoing lumbar fusion for lumbar degenerative diseases：A combination of DXA and hounsfield units［J］.Spine，2020，45(7)：E406-E410.
［9］Pappou IP，Girardi FP，Sandhu HS，et al.Discordantly high spinal bone mineral density values in patients with adult lumbar scoliosis［J］.Spine，2006，31(14)：1614-1620.
［10］de Vries AA，Mullender MG，Pluymakers WJ，et al.Spinal decompensation in degenerative lumbar scoliosis［J］.Eur Spine J，2010，19(9)：1540-1544.
［11］Wu HL，Ding WY，Shen Y，et al.Prevalence of vertebral endplate modic changes in degenerative lumbar scoliosis and its associated factors analysis［J］.Spine，2012，37(23)：1958-1964.
［12］曾岩，陈仲强，郭昭庆，等.腰椎管狭窄症伴退变性腰椎侧凸患者的影像学表现与临床特点［J］.中国脊柱脊髓杂志，2007，17(10)：753-756.
［13］Bao H，Zhu F，Liu Z，et al.Coronal curvature and spinal imbalance in degenerative lumbar scoliosis：disc degeneration is associated［J］.Spine，2014，39(24)：E1441-1447.
［14］吴海龙，郭尔斐，张帅，等.退变性腰椎侧凸患者矢状面平衡的特点及对腰椎侧凸的影响［J］.中国脊柱脊髓杂志，2019，29(1)：16-20.
［15］Hong JY，Suh SW，Modi HN，et al.The prevalence and radiological findings in 1347 elderly patients with scoliosis［J］.J Bone Joint Surg (Br)，2010，92(7)：980-983.
［16］翟睿，汪学松，金传峰，等.退变性脊柱侧弯与骨质疏松症相关性分析［J］.中国骨质疏松杂志，2014，20 (3)：256-259.
［17］黄道余，沈亚骏，王飞，等.退行性腰椎侧凸与骨质疏松症的相关性分析［J］.中国骨伤，2019，32(3)：244-247. |
|
|
���������� 14010702070875��