颈椎钩椎关节融合器初始稳定性生物力学测试

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摘要目的测试颈椎钩椎关节融合器的初始稳定性。方法将20具山羊颈椎标本随机分为完整颈椎组、自体髂骨块植入组、钩椎关节融合器植入组、传统椎间融合器植入组四组，采用非破坏弹性法对山羊C_3～4节段进行过伸/过屈、左右侧屈以及轴向旋转活动范围(range of motion，ROM)测试。结果钩椎关节融合器组、零切迹融合器对照组在前屈、后伸、左右侧屈、轴向旋转维度上角位移与髂骨块植入组均差异有统计学意义(P＜0.05)；钩椎关节融合器组和零切迹融合器对照组过伸/过屈ROM差异无统计学意义(P＞0.05)，但钩椎关节融合器组左右侧屈ROM和左右旋转ROM略小于零切迹融合器对照组，差异有统计学意义(P＜0.05)。结论钩椎关节融合器在左右侧屈与轴向旋转方面稳定性略优于传统零切迹椎间融合器，在前屈/后伸方面与传统零切迹椎间融合器稳定性相当。

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关键词 ：钩椎关节融合器, 颈椎, 初始稳定性, 生物力学, 山羊

Abstract：Objective To test the biomechanicalinitial stability of the uncovertebral joint fusion cage.Methods 20 goat cervical specimens were randomly assigned to 4 groups：Group A，the intact cervical spine group；Group B，the iliac bone group；Group C，the uncovertebral joint fusion cage group；Group D，the non-profile cage control group.The specimens were exposed to nondestructive testing in all 3 planes of spinal motion：extension/flexion，lateral bending and axial rotation，using the moment of force 1 N·m，2 N·m，3 N·m，and 4 N·m.The flexibility method was used for evaluation of stability，and nonconstrained pure moment bending load was applied for three loading and unloading cycles in each plane，while the data of the final cycle was recorded for analysis of range of motion (ROM).Results The ROM of extension/flexion，lateral bending and axial rotation in the uncovertebral joint fusion cage group and the non-profile cage control group were both smaller than the iliac bone group(P＜0.05).There was no significant difference concerning ROM of extension/flexion between the uncovertebral joint fusion cage group and the non-profile cage control group.The ROM of lateral bending and axial rotation in the uncovertebral joint fusion cage group was smaller than the non-profile cage control group(P＜0.05).Conclusion The uncovertebral joint fusion cage and the non-profile cage can both provide better initial stability compared the iliac bone.The uncovertebral joint fusion cage can provide similar initial extension/flexion stability but a little better lateral bending and axial rotation stability compared with the non-profile cage.

Key words： uncovertebral joint fusion cage cervical spine initial stability biomechanical test goat

基金资助:四川大学华西医院学科卓越发展1·3·5工程项目(ZYJC18029)
四川省科技厅重点研发项目(2018SZ0042)
中国博士后基金第11批特别资助(2018T110979)

通讯作者: 刘浩

作者简介: 杨毅(1990－ )，男，医师，四川大学华西医院骨科，610041。

引用本文:

杨毅 1，罗帅 2*，刘浩 1*，吴廷奎 1，胡凌云 1，陈林 1，李广州 1，孟阳 1. 颈椎钩椎关节融合器初始稳定性生物力学测试[J]. 实用骨科杂志, 2019, 25(11): 986-990.
Yang Yi 1，Luo Shuai 2*，Liu Hao 1*，et al. Biomechanicalinitial Stabilitytest of the Uncovertebral Joint Fusion Cage. sygkzz, 2019, 25(11): 986-990.

链接本文:

http://www.sygkzz.com/CN/ 或 http://www.sygkzz.com/CN/Y2019/V25/I11/986

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