Abstract:Objective To analyze the risk factors of surgical site infection in Pilon fracture.Methods From January 2005 to December 2019,621 patients with Pilon fracture were treated with open reduction and internal fixation.According to the surgical site infection,the patients were divided into two groups:infection group (n=39),including male (n=26) and female (n=13),with an average age of (43.4±13.5)years(range from 20 to 72 years),and non-infection group (n=582),including 303 males and 279 females,with an average age of (42.1±12.0)years(range from 19 to 71 years).Age,sex,smoking,BMI,diabetes,alcohol consumption,hypertension,soft tissue injury,operation time,blood transfusion,and drainage time were included in the possible risk factors.The statistical method was univariate analysis first,and then multivariate Logistic regression analysis was used to analyze the significant risk factors.Results The rate of surgical site infection of Pilon fracture was 6.28%.Univariate analysis showed that there were significant differences in diabetes,operation time and soft tissue injury between infection group and non-infection group,while multivariate Logistic regression analysis found that only operation time was significantly correlated with operation site infection (P<0.01).Conclusion Operation time is an independent predictor of surgical site infection after open reduction and internal fixation of Pilon fracture.Although severe soft tissue injury can increase the infection rate of surgical site,it is not an independent predictor of surgical site infection after open reduction and plate internal fixation of Pilon fracture.
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