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2023 Vol. 29, No. 11
Published: 2023-11-25
961
Feasibility Analysis of Predicting the Clinical Effect of Single Open Door Laminoplasty in the Treatment of Ossification of the Posterior Longitudinal Ligament By the Preoperative K Line Tilt
Wang Chunzeng,Zhang Jianwei,Hu Menzi,Han Meng,Zhang Zhaochuan,Li Jie,Liu Guangwang
Objective
To explore the feasibility of predicting the clinical effect of single open door laminoplasty in the treatment of ossification of the posterior longitudinal ligament by the preoperative K line tilt.
Methods
The data of 52 patients with ossification of the posterior longitudinal ligament (OPLL) with positive K line who were treated by posterior cervical singledoor laminoplasty from February 2019 to January 2022 were analyzed retrospectively.35 male and 17 female were included.The patients age from 47 to 76 years,with an average of (61.46±7.26)years.The score of the Japanese orthopedic association (JOA) before the operation and the JOA score at the oneyear followup after the operation were recorded.The parameters of sagittal plane before operation were measured on the neutral lateral radiograph of cervical spine,which including Kline tilt,C
2~7
Cobb angle,C
2~7
sagittal vertical axis (C
2~7
SVA),center gravity of head (CGH) ~ C
7
sagittal axial distance (CGH~C
7
SVA),T
1
slope.According to the median JOA score 1 year after surgery,patients were divided into good improvement group and poor improvement group.The preoperative K-line tilt and other sagittal plane parameters were used as independent variables.One-way analysis of variance and Logistic regression were used to analyze the risk factors affecting the postoperative JOA improvement rate.
Results
The clinical symptoms of all patients were improved.The preoperative C
2~7
Cobb angle was (14.45±8.81)°,C
2~7
SVA was (15.31±4.57)mm,CGH~C
7
SVA was (16.37±5.23)mm,T
1
slop was (26.43±5.65)°,K-line tilt was (12.77±1.49)° and preoperative JOA score of OPLL patients were (7.38±0.89) points.According to the improvement rate of JOA score at 1 year follow-up,the analysis of preoperative cervical sagittal parameters after grouping showed that the preoperative kline tilt,preoperative C
2~7
SVA,preoperative CGH~C
7
SVA (
P
<0.001,
P
=0.013,
P
=0.022) were closely related to the postoperative efficacy,and the preoperative K-line tilt was positively correlated with C
2~7
SVA,CGH~C
7
SVA(r=0.411,r=0.831,
P
=0.004,
P
=0.023).Logistic regression analysis showed that preoperative K-line tilt and preoperative CGH~C
7
SVA (OR=1.673,OR=1.522,
P
=0.024,
P
=0.033) were the risk factors affecting postoperative efficacy.
Conclusion
The postoperative efficacy of patients with OPLL is related to the preoperative K line tilt.The patients with large preoperative K line tilt have poor postoperative efficacy.The K line tilt can be used as a new clinical index to predict the postoperative efficacy of patients with OPLL before single-door surgery through the posterior cervical spine.
2023 Vol. 29 (11): 961- [
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966
Analysis of the Survival Rate and Risk Factors of Vertebral Body Refracture After Percutaneous Vertebroplasty
Xuan Chong,Wang Hongliang,Zhou Tao
Objective
To determine the natural course of new vertebral fractures after vertebroplasty,analyze the associated risk factors,and investigate the incidence and correlation between adjacent vertebral fracture (AVF) and remote vertebral fracture (RVF).
Methods
A retrospective analysis was conducted on the clinical data of 260 patients who underwent percutaneous vertebroplasty augmentation surgery in Ma'anshan People’s Hospital from January 2018 to January 2021.75 patients were male and 185 patients were female,with an age range of 62~81 years and a mean age of (67.34±7.21)years.Patients were divided into fracture group and control groups based on the presence or absence of vertebral fractures during a follow-up period of at least 2 years post surgery.The fracture group was further divided into AVF and RVF groups,based on the relationship between the fractured vertebrae and the operated vertebrae.Survival analysis and regression analysis of various risk factors were employed to examine potential differences in occurrence time and risk factors between AVF and RVF.
Results
Among the 260 patients included in the study,a total of 55 patients presented with newly developed vertebral fractures.42 patients involved adjacent vertebrae,and the average time of onset was (6.2±2.4)months.Furthermore,there were 13 cases of distant fractures,with an average onset time of (12.3±1.6)months.Both singlefactor and multi factor Cox regression analyses were conducted to identify risk factors for AVF and RVF.The results revealed that CT value,treatment with anti osteoporosis drugs,and sagittal imbalance were significant risk factors for AVF (
P
<0.05).Additionally,CT value was identified as a risk factor for RVF (
P
<0.05).
Conclusion
The occurrence of AVF is significantly earlier than that of RVF in patients after percutaneous vertebroplasty.The independent risk factors for AVF include CT values,treatment with anti osteoporotic drugs and sagittal plane imbalance.CT values also serve as a common risk factor for both AVF and RVF.
2023 Vol. 29 (11): 966- [
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970
Effects of Controlled Hypotension on Blood Loss and Bone Cement Penetration Thickness in Total Knee Arthroplasty
Li Xinglong,Liu Jiawei,Cheng Jianjun,Ding Ya,Cai Ning,Yu Haiyang,Wang Hongliang
Objective
To compare the blood loss and bone cement penetration thickness after total knee arthroplasty under controlled hypotension and tourniquet.
Methods
retrospective study was conducted to collect 168 patients in the Fuyang Hospital Affiliated to Bengbu Medical College.The patients underwent unilateral total knee arthroplasty under general anesthesia from January 2020 to December 2022.According to different methods of intraoperative hemostasis,they were divided into a controlled hypotension group and a tourniquet group.The controlled hypotension group had 61 cases.Among them,there were 17 males and 44 females.The patients aged 55 to 80 years,with an average age of (67.26±5.56)years.The tourniquet group had 107 cases.Among them,there were 28 males and 79 females.The patients aged 55~80 years,with an average age of (67.70±5.81)years.There was no statistically significant difference between the two groups in general information such as gender,age,height,weight,body mass index,and preoperative hemoglobin and hematocrit (
P
>0.05).The differences in blood loss data,surgical time,and bone cement infiltration thickness around the tibial prosthesis were compared between the two groups.
Results
There was no statistically significant difference between the two groups in surgical time,dominant blood loss,and bone cement infiltration thickness around the tibial prosthesis (
P
>0.05).There was a statistically significant difference between the two groups in hemoglobin reduction,hematocrit reduction,intraoperative bleeding,postoperative drainage,hidden blood loss,and total blood loss (
P
<0.05).
Conclusion
Compared to using a tourniquet during surgery,the use of controlled hypotension can reduce the patient’s hidden blood loss and total blood loss,without increasing the surgical duration,and without affecting the bone cement penetration thickness around the tibial prosthesis in total knee arthroplasty.
2023 Vol. 29 (11): 970- [
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132
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975
Application of Multi-site Osteotomy Combined with Ilizarov Technique for Correction of Severe Knee Varus Deformity in Adolescents
Li Xiaofan,Liang Da,Wu Mingyu,Ma Zhen,Zhang Kai,Zhong Wei
Objective
To examine the clinical efficacy of multilevel osteotomy and the Ilizarov technique to correct genu valgum deformities in adolescents.
Methods
Thirteen adolescents (15 knees) with severe genu valgum deformities were treated with multilevel osteotomy and Ilizarov external fixation apparatus at the Department of Orthopaedics in the Affiliated Hospital of Weifang Medical University between September 2019 and March 2021.8 patients were male (61.54%),and 5 patients were female (38.46%).Their ages ranged from 9 to 17 years,with an average age of (13.57±2.71)years.The deformities affected the left knee in 9 cases (60%) and the right knee in 6 cases (40%).We compared various parameters,including anatomic femurtibia angle (aFTA),lateral distal femoral angle (LDFA) and medial proximal tibial angle (MPTA) before the surgery,at 3 months post-surgery,at 6 months post-surgery,and at the last follow-up.Knee joint range of motion,Oxford knee score (OKS),and hospital for special surgery (HSS) knee-rating scale before surgery and at the last follow-up were also compared.
Results
Thirteen patients (15 knees) with knee joint deformities were followed up for a duration of 24 to 39 months,with an average follow-up time of (29.63±3.29)months.In comparison to the preoperative measurements,aFTA and LDFA showed significant reductions at 3 months,6 months,and the last follow-up (
P
<0.001),while MPTA significantly increased (
P
<0.001).Compared to the preoperative status,the knee range of motion in the patients exhibited no significant abnormalities at the last follow-up (
P
>0.05),the OKS significantly decreased (
P
<0.001),and the score of HSS significantly improved (
P
<0.001).
Conclusion
The use of multilevel osteotomy in combination with the Ilizarov technique demonstrates significant efficacy in treating genu valgum deformities in adolescents.This treatment approach can yield highly satisfactory results.
2023 Vol. 29 (11): 975- [
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138
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980
The Clinical Outcomes of Cutting Guides Assisted High Tibial Osteotomy Compares to Traditional Osteotomy
Liu Yuan,Liu Jian,Huang Ye,Wang Xingshan,Liu Qing,Cui Yanan,Liu Gang,Wan Yebiao
Objective
To compare the clinical outcomes of 3D printed cutting guides assisted open wedge high tibial osteotomy (OWHTO) to OWHTO with classic AO technique.
Methods
The clinical data of 98 patients from March to December 2020 were screened and a total of 90 patients met the grouping criteria and were randomized grouping by the random number list provided by PASS software.Finally,45 patients (70 knees) were selected for study group.The patients consisted of 25 males and 20 females,with ages ranging from 19~69 years,mean age (40.48±14.95)years.Patients in study group treated by 3D printed cutting guides assisted high tibial osteotomy (HTO) Another 45 patients (59 knees) were selected for control group.The patients consisted of 19 males and 26 females,with ages ranging from 21~71 years,mean age (48.16±16.65)years.Patients in control group treated by HTO with classical AO technique.The target alignments were planned and recorded before surgery.The differences between the postoperative alignments and the planned target alignments were compared in two groups.Postoperative posterior tibial slope (PTS),operation time and intraoperative fluoroscopy times were recorded.The differences between preoperative and postoperative Oxford knee score (OKS) were also compared between two groups.
Results
Intraoperative fluoroscopy times in study group (13.79±8.12) was statistically significant less than control group (23.36±11.80) (
P
<0.01).There was no significant difference of postoperative and target weight bearing line ratio (WBLR) in study group (4.29±4.57)% and control group (4.75±4.87)% (
P
=0.62).The proportion of patients whose difference between postoperative and target WBLR within ±10% was 75.81% in study group and 73.33% in control group.There was no significant difference between two groups (
P
=0.82).There was no significant difference of postoperative and target posterior tibial slope (PTS) in study group (3.16±4.62)° and control group (1.86±2.39)° (
P
=0.10).The improvement of OKS in study group (4.27±10.14) was statistically significant higher than control group (-1.83±12.67) (
P
<0.01).
Conclusion
Comparing to HTO with classic AO technique,3D printed cutting guides can significantly decrease the intraoperative fluoroscopy times and increase the postoperative OKS.
2023 Vol. 29 (11): 980- [
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139
)
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985
Efficacy Comparison of Two Surgical Approaches in the Treatment of Hyperextension Tibial Plateau Fracture
Wang Libing,Shang Jin,Yang Huifeng,Guo Xiuzhen,Wang Dongdong,Qi Zhengxi,Qiao Xiaohong
Objective
To compare the clinical efficacy of anteromedial combined anterolateral approach and posteromedial combined anterolateral approach in the treatment of hyperextension tibial plateau fracture.
Methods
Data of 72 patients with hyperextension tibial plateau fracture treated with anteromedial or posteromedial combined anterolateral approach in the Department of Orthopedics of Luliang People’s Hospital from April 2018 to April 2022 were retrospectively analyzed,and they were divided into group A and group B according to treatment methods.Patients of Group A underwent anteromedial combined anterolateral approach surgeries.Group A had 35 patients,including 25 males and 10 females.The patients aged 20~73 years,with an average age of (46.31±14.56) years.Patients of Group B underwent posteromedial combined anterolateral approach surgeries.Group B had 37 patients,including 26 males and 11 females.The patients aged 23~73 years,with an average age of (45.30±14.51) years.Operation time,intraoperative blood loss,weightbearing activity time,visual analogue scale (visualanaloguescale,VAS) and postoperative complication rates were compared to assess the clinical efficacy of two groups.American hospital for special surgery (hospitalforspecialsurgery,HSS) Knee joint scoring criteria were used to assess knee joint function.The changes of posterior inclination and varus Angle of tibial plateau were evaluated by X-ray.
Results
All 72 patients were followed up for 12~28 months,with an average of (17.93±4.13) months.All fractures healed clinically and the function of knee joint returned to normal.There was no statistically significant difference in knee HSS score between the two groups at 6 months after surgery (
P
>0.05),but the knee HSS score of group A was lower than that of group B at 12 months after surgery,the difference was statistically significant (
P
<0.05),and the excellent and good knee function rate of group A was significantly lower than that of group B,the difference was statistically significant (
P
<0.05).The operative time,intraoperative blood loss,postoperative 1 d and 3 d VAS scores and posterior inclination of tibial plateau in group A were higher than those in group B.The time of weightbearing activity and the varus Angle on the day after operation in
group B were higher than those in group A,and the difference was statistically significant (
P
<0.05).
Conclusion
The short-term follow-up treatment of hyperextension tibial plateau fracture using the posteromedial combined anterolateral approach is more effective.Due to the small number of cases and lack of long-term follow-up results,further observation and study are needed.
2023 Vol. 29 (11): 985- [
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989
Platelet Rich Plasma Combined with MIPPO Technique in Treatment of Tibial Closed Fracture
Sun Binglong,Zhou Lifang,Dong Guixin,Cong Haibo
Objective
To investigate the effect of minimally invasive percutaneous plate osteosynthesis (MIPPO) combined with plateletrich plasma(PRP) for tibial shaft closed fractures.
Methods
A total of 62 patients with freshly closed tibial shaft fractures admitted to Weihai Central Hospital affiliated to Qingdao University from January 2019 to May 2020 were selected.Patients were divided into control group and treatment group according to random number table method,with 31 cases in each group.The treatment group with minimally invasive percutaneous plate fixation MIPPO at the same time of fracture end applications of PRP treatment.The control group was treated with MIPPO alone without PRP.In the treatment group,there were 19 males and 12 females.The average age was (38.48±12.01)years,ranging from 19~60 years.In the control group,there were 21 males and 10 females.The average age was (39.77±12.31)years,ranging from 19~57 years.Operation time,intraoperative blood loss,fracture healing time,complete weightbearing time,complications,JohnerWruhs excellent and good rate 12 months after surgery were recorded and compared between the two groups.
Results
All patients were followed up for more than 12 months.The complete weight-bearing time,fracture healing time and incision healing in the treatment group were better than those in the control group,and the differences were statistically significant (
P
<0.05).The curative effect was evaluated by Johner-Wruhs criteria 12 months after surgery.In the treatment group,27 cases were excellent,2 cases were good,and 2 cases were medium,with an excellent and good rate of 93.55%.In the control group,19 cases were excellent,3 cases were good,5 cases were medium,and 4 cases were poor,with an excellent and good rate of 70.97%.The therapeutic effect of the treatment group was better than that of the control group,and the difference was statistically significant (
P
<0.05).All fractures healed in the treatment group,and no obvious complications occurred after operation.One case of superficial infection in control group was cured by dressing change.Delayed fracture of union was observed in 1 patients,and the fracture healed until 11 months after surgery.
Conclusion
PRP combined with MIPPO technique can significantly shorten fracture healing time,reduce delayed fracture healing,reduce postoperative complications,and improve the functional activity of the affected limb,without obvious complications,which has clinical application value.
2023 Vol. 29 (11): 989- [
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131
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994
Modulation of Osteoblast Biological Behavior by 3D Printed Triply Periodic Minimal Surfaces Primitive Scaffolds with Different Pore Sizes
Cheng Debin,Zhang Zhao,Fu Jun,Liu Dong,Fan Hongbin
Objective
To explore the effects of different pore sizes of 3D printed triply periodic minimal surfaces (TPMS) primitive scaffolds on the proliferation and differentiation of osteoblasts MC3T3E1,and to provide a theoretical basis for the design of subsequent 3D printed personalized prosthetic porous structures.
Methods
Design and fabrication of TPMS substrate scaffolds with three pore sizes (400 μm,600 μm and 800 μm) were conducted based on TPMS implicit surface functions and selective laser melting (SLM).The scaffolds with different pore sizes were co-cultured with osteoblasts MC3T3-E1 and their effects on osteoblast proliferation and differentiation were evaluated by CCK-8,Cytoskeleton staining,alkaline phosphatase activity and western blot (WB) analysis.
Results
Scanning electron microscopy showed that TPMS primitive scaffolds with different pore sizes were successfully fabricated and osteoblasts MC3T3-E1 showed good adhesion in the scaffolds.The results of CCK-8 experiments indicated that the proliferation of MC3T3-E1 increased significantly with increasing pore size.In addition,the TPMS primitive scaffold exhibited the highest alkaline phosphatase activity at a pore size of 600 μm.WB analysis further revealed that the expression of collagen type Ⅰ(Col Ⅰ),Runt related transcription factor 2(Runx2) and osteopontin (OPN) proteins were also highest in the 600 μm group.
Conclusion
As the pore size increased,the 3D printed TPMS scaffold demonstrates enhanced osteoblast proliferation.Furthermore,a pore size of 600 μm is optimal for osteoblast differentiation.
2023 Vol. 29 (11): 994- [
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