青年人群腰椎间盘突出症与多发性关节松弛的相关性研究

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Abstract Objective To analyze the influencing factors of lumbar disc herniation in young people and the influence of multiple joint laxity on lumbar spine stability in patients with lumbar disc herniation.Methods According to the inclusion and exclusion criteria，60 patients with lumbar disc herniation in our hospital from December 2019 to November 2020 were selected as the observation group，and 60 healthy volunteers as the control group.In the observation group，there were 32 males and 28 females；the average age was (33.87±4.31)years；21 cases had body mass index(BMI)<24 kg／m²，and 39 cases≥24 kg／m².In the control group，there were 29 males and 31 females；the average age was (34.46±3.16)years；29 cases had BMI<24kg／m² and 31 cases≥24 kg／m².The general information and Beighton scores of the two groups were statistically analyzed.At the same time，measure the angular displacement，horizontal displacement，pelvic incidence(PI)，pelvic tilt(PT)，sacral slope(SS)，and anterior lumbar disc herniation on X-ray films.Lump(lumbar lordosis，LL).According to the Beighton score，patients with lumbar disc herniation were divided into nonmultiple joint laxity group and multiple joint laxity group，and their general data and imaging parameters were analyzed in subgroups.Results There were no statistically significant differences in gender，age，smoking history between the observation group and the control group (P＞0.05).The observation group had a higher BMI，and the difference was statistically significant compared with the control group (P＜0.05).The incidence of multiple joint laxity in the control group was 35.00%，which was much higher than the control group's 15.00%，and the difference was statistically significant (P＜0.05).In the multivariate logistic analysis，high BMI and multiple joint laxity were risk factors for lumbar disc herniation.In the subgroup analysis，there were 39 cases in the non-multiple joint relaxation group and 21 cases in the multiple joint relaxation group.There was no significant difference in gender，age，smoking history，BMI，and course of disease between the two groups (P＞0.05)；horizontal displacement in the multiple joint relaxation group Angular displacement and SS were larger than those in the non-multiple joint laxity group (P＜0.05).There was no significant difference between the PI，LL，and PT groups (P＞0.05).Conclusion Multiple joint laxity is an important risk factor for lumbar disc herniation in young patients，and it has a negative impact on the stability of the lumbar spine.

Key words： lumbar disc herniation multiple ligament laxity correlation study

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［1］Wang GJ，Peng JM，Cai KM，et al.Epidemiological study on the pathogenic factors of lumbar disc herniation［J］.Prev Med，2009(36)：2401-2403.
［2］Vialle LR，Vialle EN，Suárez Henao JE，et al.Lumbar disc herniation［J］.Rev Bras Ortop，2015，45(1)：17-22.
［3］吕振，白金柱.基于McKenzie技术的腰椎运动链训练应用于腰椎间孔镜术后分期康复的前瞻性研究［J］.中国组织工程研究，2021，25(9)：1398-1403.
［4］李瀚卿，施荣茂，周强，等.腰椎融合辅以邻近节段动态固定治疗腰椎退行性疾病的早期临床疗效观察［J］.脊柱外科杂志，2014，12(1)：5-10.
［5］Kirk JA，Ansell BM，Bywaters EG.The hypermobility syndrome.Musculoskeletal complaints associated with generalized joint hypermobility［J］.Ann Rheum Dis，1967，26(5)：419-425.
［6］Carbone F，Fikree A，Aziz Q，et al.Joint hypermobility syndrome in patients with functional dyspepsia［J］.Clin Transl Gastroenterol，2020，11(11)：e00220.
［7］Grahame R.Joint hypernmbility and genetic collagen disorders：are they related?［J］.Arch Dis Child，1999，80(2)：188-191.
［8］Yang Y，Yan X，Li W，et al.Long-term clinical outcomes and pain assessment after posterior lumbar interbody fusion for recurrent lumbar disc herniation［J］.Orthop Surg，2020，12(3)：907-916.
［9］Adib N，Davies K，Grahame R，et al.Joint hypermobility syndrome in childhood.A not so benign multisystem disorder?［J］.Rheumatology(Oxford)，2005，44(6)：744-750.
［10］Dupuis PR，YongHing K，Cassidy JD，et al.Radiologic diagnosis of degenerative lumbar spinal instability.［J］.Spine，1985，10(3)：262-276.
［11］Schwab FJ，LafageR，LiabaudB，et al.Does one size fit all? Defining spinopelvic alignment thresholds based on age［J］.Spine J，2014，14(11)：120-121.
［12］Lee GW，Lee SM，Suh BG.The impact of generalized joint laxity on the occurrence and disease course of primary lumbar disc herniation［J］.Spine J，2015，15(1)：65-70.
［13］沈祥，徐宏光，马明明，等.脂肪间充质干细胞注入退变椎间盘局部的作用［J］.中国组织工程研究，2017，21(1)：77-81.
［14］李渊，石俊俊，任捷，等.肥胖与青少年腰椎间盘突出症发病关系［J］.中国骨伤，2020，33(8)：725-729.
［15］Axelsson P，Karlsson BS.Intervertebral mobility in the progressive degenerative process.A radiostereometric analysis［J］.Eur Spine J，2004，13(6)：567-572.
［16］Gensemer C，Burks R，Kautz S，et al.Hypermobile Ehlers-Danlos syndromes：Complex phenotypes，challenging diagnoses，and poorly understood causes［J］.Dev Dyn，2021，250(3)：318-344.
［17］Khosehnau S，Melhus H，Jacobson A，et al.Type I collagen alphalSpl polymorphism and the risk of cruciate ligament ruptures or shoulder dislocations［J］.Am J Sports Med，2008，36(12)：2432-2436.
［18］Chen HC，Shah SH，Li YJ，et al.Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels［J］.Arthritis Rheum，2008，58(12)：3854-3864.
［19］Malfait F，Hakim AJ，De Paepe A，et al.The genetic basis of the joint hypermobility syndromes［J］.Rheumatology，2006，45(5)：502-507.
［20］McKusick VA.Theehiers-daniossyndrome［M］//Heritabie disorders of Connective tissue.4th ed.Louis：Mosby，1972：292-371.
［21］Beighton P，De Paepe A，Steinmann B，et al.Ehlers-Danlossyndromes：revised nosology，Villefranche，1997.Ehlers DanlosNational Foundation(USA)and Ehlers Danlos Suppog Group(UK)［J］.Am J Med Genet，1998，77(1)：31-37.
［22］刘洋，李明，朱晓东，等.EhlersDanlos综合征合并脊柱侧凸外科治疗附2例报告及文献复习［J］.脊柱外科杂志，2007，5(1)：44-46.
［23］Grahame R，Edwards JC，Pitcher D，et al.A clinical and echocardiographic study of patients with the hypermobility syndrome［J］.Ann Rheum Dis，1981，40(6)：541-546.
［24］Sacks HA，Prabhakar P，Wessel LE，et al.Generalized joint laxity in orthopaedic patients：Clinical manifestations，Radiographic Correlates，and Management［J］.J Bone Joint Surg (Am)，2019，101(6)：558-566.
［25］Tinkle BT.Symptomatic joint hypermobility［J］.Best Pract Res Clin Rheumatol，2020，34(3)：101508.
［26］Franklin CC，Weiss JM.The natural history of pediatric and adolescent shoulder dislocation［J］.J Pediatr Orthop，2019，39(Suppl 1)：S50-S52.
［27］Han WJ，Kim HB，Lee GW，et al.Generalized joint laxity is associated with primary occurrence and treatment outcome of lumbar disc herniation［J］.Korean J Fam Med，2015，36(3)：141-145.
［28］Cooley JR，Walker BF，Ardakani EM，et al.Relationships between paraspinal muscle morphology and neurocompressive conditions of the lumbar spine：A systematic review with meta-analysis［J］.BMC Musculoskelet Disord，2018，19(1)：351.
［29］李杰，张杰锋，李益明，等.椎间孔镜术中骨钻与环锯关节突成形的比较［J］.中国矫形外科杂志，2019，27(7)：597-601.