Establishment of Novel Artificial Cervical Disc Goat Model and Related Study
1.Department of Orthopaedics,West China Hospital,Sichuan University
2.Department of Orthopaedics,Southwest Hospital,The Third Military Medical University
Abstract:Objective To observe the effect of novel domestic-made artificial cervical disc in vivo with goat model,in order to provide an experimental basis for further improvement and clinical application.Methods 12 male experimental goats underwent C3~4 novel domestic-made artificial cervical disc replacement.All the goats were examined preoperatively and postoperatively on anteroposterior and lateral radiographs.The disc height (DH),intervertebral angle (IVA) and functional spinal unit (FSU) lordosis angle were measured and analyzed statistically.Results All experimental goats survived after operation,without incision infection and paralysis.Hoarseness occurred in one goat the second day after operation,and disappeared one week later.Statistical comparison in DH,IVA and FSU lordosis angle at C3~4 segment showed no significant difference among different time points.Conclusion Novel domestic-made artificial cervical disc system is easy to operate,has less complications,and can maintain the postoperative disc height and cervical spinal curvature well.
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