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Abstract Objective To investigate the effect of ultrasound guided target injection of mecobalamin on nerve electrophysiology，nerve structure under ultrasound and sensory function after peripheral nerve injury.Methods In this study，patients with dysfunction after peripheral nerve injury were randomly divided into the experimental group and the control group at a ratio of 1︰1.There were 13 cases (9 males and 4 females) in the experimental group，with an average age of (33.92±7.54），and 12 cases (9 males and 3 females) in the control group，with an average age of (33.08±11.31).The experimental group received ultrasoundguided target injection of mecobalamin injection combined with conventional therapy，while the control group received conventional therapy.Results were assessed with the nerve electrophysiology (neural latency，amplitude，conduction velocity)，nerve diameter and crosssectional area under ultrasound，and the british medical research council (BMRC) sensory function assessment before treatment and after 12 weeks of treatment.Results Compared with before treatment，the two after treatment groups had statistically significant difference in nerve electrophysiology，nerve diameter and cross sectional area under ultrasound，and nerve BMRC sensory assessment(P＜0.05).Compared with the control group，the difference was statistically significant in the changes of nerve diameter and cross sectional area and nerve BMRC sensation before and after treatmentin the experimental group (P＜0.05).Conclusion Ultrasound guided targeted injection of mecobalamin combined with conventional therapy is better in improving peripheral nerve structure and sensory function than conventional therapy.
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Corresponding Authors:
Yang Ying
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