椎体脂肪化对椎体骨质疏松性骨折风险的评价意义

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Abstract Objective To investigate the role of MRI vertebral fat fraction in the prediction of vertebral osteoporotic fracture (VOF).Methods The study aimed to collect patient data from April 2016 to June 2021 who underwent percutaneous kyphoplasty (PKP) treatment for pathologic bone fracture caused by osteoporosis，as well as examine patients during the same period.A total of 168 patients were matched based on gender and age and divided into fracture and non fracture groups.58 male and 110 female patients were included，with ages ranging from 50 to 89 years，average age of (64.78±7.32) years.Quantitative measurements were conducted on MRI images to determine the vertebral fat area ratio (VFAR)，vertebral fat signal ratio (VFSR)，and vertebral fat index (VFI).Singlefactor comparisons were made between the two groups to analyze the correlation between vertebral body steatosis and vertebral osteoporotic fracture (VOF).Further subgroup analyses were conducted based on gender and age，followed by pairedsample ttests between the fracture and non-fracture groups.The diagnostic efficiency of VFAR，VFSR，and VFI for VOF was also assessed using the ROC curve.Results The fracture group's VFAR，VFSR，and VFI were significantly higher than the non-fracture group's (P＜0.05).The VOF area under the ROC curve as determined by VFAR is 0.643 0，and the critical value for fracture diagnosis was 0.157 6.The area under the ROC curve for VOF as determined by VFSR was 0.580 8，and the critical value for fracture diagnosis was 0.741 5.The area under the ROC curve for VOF as determined by VFI was 0.645 5，and the critical value for fracture diagnosis was 0.102 2.Conclusion Adiposity of the vertebral body is an important risk factor for the development of VOF in patients，and it has some value in VOF diagnosis.

Key words： lumbar spine osteoporosis vertebral body steatosis osteoporotic fracture

Corresponding Authors: Qian Yu

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	Xu Rongjian
	Zheng Jiewen
	He Lei
	Qian Yu

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Xu Rongjian,Zheng Jiewen,He Lei, et al. Evaluation of the Significance of Vertebral Body Steatosis on the Risk of Vertebral Osteoporotic Fracture[J]. sygkzz, 2023, 29(5): 395-.

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http://www.sygkzz.com/EN/ OR http://www.sygkzz.com/EN/Y2023/V29/I5/395

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