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Abstract Objective To analyze the early curative effect and safety of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in the treatment of lumbar spondylolisthesis.Methods 60cases of lumbar spondylolisthesis patients treated in our hospital during January 2015 to June 2017 were recruited in this study and randomly divided into observation group and control group.30 patients in observation group wase given MIS-TLIF surgical intervention,while another 30 patients in control group was given conventional posterior lumbar intervertebral fusion (PLIF).All the patients were followed up for least 3 months after operation.The difference of operation time,intraoperative blood transfusion and postoperative suction drainage between two groups were compared.Plain lumbar spine X-ray or CT examination was conducted preoperative and 3 months after operation to observe the change of spondylolisthesis in two groups.VAS and ODI scoring system were used to assess patients postoperative pain and lumbar function recovery before and 3 days,1month and 3 months after operation.The overall prognosis and fine rate were caculated according to the MacNab standard.Results The operating time in observation group was longer than control group,while the bed time,hospitalization time,intraoperative blood transfusion and postoperative suction drainage were lower than the control group (P<0.05).The spondylolisthesis were 5.53° and 5.42° in two groups,while they were descended to 1.31°and 1.35°respectively.In two groups,there was statistical difference before and after operation(P<0.05),while with no statistical difference between two groups(P>0.05).The VAS and ODI scores in observation group 3 days,1 month and 3month after operation were lower than that of control group (P<0.05).The fine rate in observation group was 86.67% and higher than 63.33% in control group (P<0.05).The incidence of complications,observation group was 6.67%,while the control group was 10.00%.There was no statistically significant difference between the two groups (P>0.05).Conclusion The therapeutic effect of MIS-TLIF in the treatment of lumbar spondylolisthesis was good and helpful to lumbar functional recovery.It has the advantages of small trauma,rapid recovery,thus was worthy of clinical promotion.
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