一期后路病灶清除、椎间植骨治疗腰椎布氏杆菌性脊柱炎

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Abstract Objective To evaluate the safety and efficacy of posterior radical debridement，intervertebral fusion and internal fixation for the treatment of lumbar brucella spondylitis.Methods There were 16 cases(10 males，6 females) underwent posterior approach radical debridement，intervertebral fusion and internal fixation for the treatment of lumbar brucella spondylitis from January 2010 to January 2014.The average age was (40.6±15)years (19 to 66 years).All patients had single segment infection and had lower back pain.13 of them had persistent fever.Visual analogue scale (VAS) and Oswestry Disability Index questionnaire (ODI) were evaluated before operation andin the final follow-up.At the final follow-up，all patients underwent standard Brucella agglutination test，X-ray and computed tomography(CT) to evaluate clinical outcomes.Results 16 patients were followed up for 12 to 47 months(18.6±5.7) months.The operation time was 100 to 140 minutes (122±15)mins；blood loss was 300 to 650 mL (482±118)mL.There was nointraoperative and perioperative death，and nerve compression symptoms.13 cases with preoperative feverdid not have a fever at 10 days after operation.Compared with pre-operation，VAS and ODI were significant improved.At the final follow-up，All the patients were cured and got intervertebral fusion.Conclusion Posterior radical debridement，intervertebral fusion and internal fixation for the treatment of lumbar Brucella spondylitis is a safe and effective treatment.

Key words： lumbar brucella spondylitis posterior operation

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