新型人工颈椎间盘山羊模型的建立及其研究

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Abstract Objective To observe the effect of novel domestic-made artificial cervical disc in vivo with goat model，in order to provide an experimental basis for further improvement and clinical application.Methods 12 male experimental goats underwent C_3～4 novel domestic-made artificial cervical disc replacement.All the goats were examined preoperatively and postoperatively on anteroposterior and lateral radiographs.The disc height (DH)，intervertebral angle (IVA) and functional spinal unit (FSU) lordosis angle were measured and analyzed statistically.Results All experimental goats survived after operation，without incision infection and paralysis.Hoarseness occurred in one goat the second day after operation，and disappeared one week later.Statistical comparison in DH，IVA and FSU lordosis angle at C_3～4 segment showed no significant difference among different time points.Conclusion Novel domestic-made artificial cervical disc system is easy to operate，has less complications，and can maintain the postoperative disc height and cervical spinal curvature well.

Key words： new cervical disc prosthesis cervical disc replacement animal model animal experiment cervical curvature

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http://www.sygkzz.com/EN/ OR http://www.sygkzz.com/EN/Y2017/V23/I5/426

［1］Traynelis VC.The Prestige cervical disc replacement［J］.Spine J，2004，4(6 Suppl)：310-314.
［2］Ding C，Hong Y，Liu H，et al.Comparison of cervical disc arthroplasty with anterior cervical discectomy and fusion for the treatment of cervical spondylotic myelopathy［J］.Acta Orthop Belg，2013，79(3)：338-346.
［3］Peng CW，Yue WM，Basit A，et al.Intermediate results of the Prestige LP cervical disc replacement：Clinical and radiological analysis with minimum two-year follow-up［J］.Spine(Phila Pa 1976)，2011，36(2)：105-111.
［4］Dong L，Tan MS，Yan QH，et al.Footprint mismatch of cervical disc prostheses with Chinese cervical anatomic dimensions［J］.Chin Med J (Engl)，2015，128(2)：197-202.
［5］Kulkarni AG，Patil VM，Bangalore SK，et al.Cervical footprint anthropometry in Indian population：Implications on design of artificial disc replacement devices［J］.Asian Spine J，2016，10 (1)：20-26.
［6］Wu W，Lyu J，Liu H，et al.Wear assessments of a new cervical spinal disk prosthesis：Influence of loading and kinematic patterns during in vitro wear simulation［J］.Proc Inst Mech Eng H，2015，229 (9)：619-628.
［7］娄纪刚，刘浩，李元超，等.一种新型人工颈椎间盘置换的生物力学研究［J］.生物骨科材料与临床研究，2016，13 (3)：10-13.
［8］Lim MR，Girardi FP，Zhang K，et al.Measurement of total disc replacement radiographic range of motion：a comparison of two techniques［J］.J Spinal Disord Tech，2005，18 (3)：252-256.
［9］Cain CC，Fraser RD.Bony and vascular anatomy of the normal cervical spine in the sheep［J］.Spine (Phila Pa 1976)，1995，20 (7)：759-765.
［10］Wilke HJ，Kettler A，Wenger KH，et al.Anatomy of the sheep spine and its comparison to the human spine［J］.Anat Rec，1997，247 (4)：542-555.
［11］Kandziora F，Pflugmacher R，Scholz M，et al.Comparison between sheep and human cervical spines：an anatomic，radiographic，bone mineral density，and biomechanical study［J］.Spine (Phila Pa 1976)，2001，26 (9)：1028-1037.
［12］Heller JG，Sasso RC，Papadopoulos SM，et al.Comparison of BRYANcervical disc arthroplasty with anterior cervical decompression andfusion：clinical and radiographic results of a randomized，controlled，clinical trial［J］.Spine (Phila Pa 1976)，2009，34 (2)：101-107.
［13］R-hl K，R-hrich F.Artificial disc versus spinal fusion in the treatmentof cervical spine degenerations in tetraplegics：a comparison of clinicalresults［J］.Spinal Cord，2009，47 (9)：705-708.
［14］郭永飞，陈德玉，刘岩，等.可调控式颈椎融合固定器实验山羊模型的建立［J］.第二军医大学学报，2008，29 (3)：290-293.
［15］Lin CY，Kang H，Rouleau JP，et al.Stress analysis of the interface between cervical vertebrae end plates and the Bryan，Prestige LP，and ProDisc-C cervical disc prostheses：an in vivo image-based finite element study［J］.Spine (Phila Pa 1976)，34 (15)：1554-1560.
［16］戎鑫，刘浩，龚全，等.颈椎下终板矢状面形态分型［J］.中国矫形外科杂志，2015，23 (5)：406-411.
［17］娄纪刚，刘浩，戎鑫，等.颈椎下终板冠状面形态分型［J］.中国矫形外科杂志，2016，24(7)：648-652.
［18］Yi S，Shin DA，Kim KN，et al.The predisposing factors for the heterotopic ossification after cervical artificial disc replacement［J］.Spine J，2013，13 (9)：1048-1054.