Abstract:Objective To investigate the influencing factors of venous thromboembolism in patients with bone trauma.Methods A total of 31 652 patients with bone trauma admitted to the Department of Orthopaedics of Wendeng Osteopathic Hospital from January 2012 to December 2016 were enrolled in the study (Smoky area).Color Doppler ultrasound or venography was used to examine 1 424 cases with venous thromboembolism.Retrospective analysis of the basic data of the patients included gender,age,past medical history,smoking history,bone trauma site,DVT predilection sites and associated diseases were performed with univariate and multivariate logistic regression analysis to analyze the influencing factors.Results Of the 31 652 hospitalized patients with bone trauma,1 424 were diagnosed with complicated venous thromboembolis with an incidence of 4.50%.Among them,there were 1304 cases of DVT,and the incidence rate was 4.12%.There were 237 cases of PE,and the incidence rate was 0.74%.Univariate and multivariate logistic analysis showed that the incidence of venous thromboembolism in patients with bone trauma was asociate with age,long-term immobilization,bone trauma sites,diabetes,D-dimer levels,AIS,and ISS (P<0.05).Conclusion The incidence of venous thromboembolism in patients with bone trauma is closely related to age,need for long-term immobilization,bone trauma,diabetes and D-dimer levels.
[1]李津凯,张秀军,李俊海,等.骨折围手术期合并深静脉血栓的防治进展[J].齐齐哈尔医学院学报,2016,37(21):2699-2702.
[2]Della Rocca G,Danelli G,Randelli F,et al.Ⅱ Italian intersocietyconsensus statement on antithrombotic prophylaxis in orthopedics and traumatology[J].Minerva Anestesiol,2013,79(7):778-792.
[3]Windyga J,Zbikowski P,Ambroziak P,et al.Management of factor VⅡ-deficient patients undergoingjoint surgeries preliminary results of locally developed treatment regimen[J].Haemophilia,2013,19(1):89-93.
[4]Siboni SM,Biguzzi E,Solimeno LP,et al.Orthopaedic surgery in patients with von Willebrand disease[J].Haemophilia,2014,20(1):133-140.
[5]裴宝瑞,吴啸波,李力更,等.应用低分子肝素钙预防老年髋部骨折术前静脉血栓栓塞症的剂量研究[J].中华老年骨科与康复电子杂志,2016,2(2):76-80.
[6]陈光,李靖年.准确理解和掌握《中国骨科大手术静脉血栓栓塞症预防指南》[J].医学与哲学,2016,37(16):1-3.
[7]王淑娟,陈丽萍.创伤骨科患者对深静脉血栓形成认知的科普效果评价[J].国际护理学杂志,2016,35(6):744-747.
[8]杨林,张利召,居永平,等.股骨干骨折并发下肢深静脉血栓的危险因素分析[J].中华创伤骨科杂志,2015,17(9):751-756.
[9]曾进强,李龙,周华乔,等.骨科创伤患者手术后下肢深静脉血栓形成的影响因素及临床治疗[J].中外医学研究,2016,14(11):21-22.
[10]孟英,刘宁,薛冰蓉,等.应用凝血标志物诊断创伤骨科术后静脉血栓形成的病例对照研究[J].中华检验医学杂志,2016,39(10):751-755.
[11]魏长月.骨科创伤手术后患者并发下肢深静脉血栓的预防和治疗护理观察[J].中国实用医药,2016,11(10):238-239.
[12]陈志军.骨科创伤手术后患者并发下肢深静脉血栓的预防和治疗观察[J].中国保健营养(下旬刊),2014(5):2606-2607.
[13]程海松,吴亚军.骨科创伤手术后患者并发下肢深静脉血栓的预防和治疗[J].中国美容医学,2012,21(16):240-241.
[14]亚俊,马志坚,廖鹏,等.骨科创伤患者术后下肢深静脉血栓的因素与临床治疗[J].中国医药导报,2014,11(10):25-27.
[15]张丽华,张炯,田红,等.利伐沙班治疗伴低抗凝血酶Ⅲ肾病综合征患者静脉血栓栓塞症的疗效[J].肾脏病与透析肾移植杂志,2015,24(1):6-10.
[16]Amitrano LI,Guardascione MA,Menchise A,et al.Safety and efficacy of anticoagulation therapy with low molecular weight heparin for portal vein thrombosis in patients with liver cirrhosis[J].J ClinGastroenterol,2010,44(6):448-451.
[17]Carniel EL,Rubini A,Frigo A,et al.Analysis of the biomechanical behaviour of gastrointestinal regions adopting an experimental and computational approach[J].Comput Methods Programs Biomed,2014,113(1):338-345.
[18]莫可锦.阿加曲班和利伐沙班在急性静脉血栓形成患者中的疗效和不良反应观察[J].医药前沿,2016,6(13):224-225.
[19]de Franchis R,Baveno VI Faculty.Expanding consensus in portal hypertension:report of the Baveno Ⅵ Consensus Workshop:stratifying risk and individualizing care for portal hypertension[J].J Hepatol,2015,63(3):743-752.