Abstract:Objective To evaluate the efficacy of bone cement augmentation of pedicle screw fixation combined with kyphoplasty for stage Ⅲ kummell disease.Methods Between August 2012 and August 2016,25 cases of stage Ⅲ kummell disease were treated by bone cement augmentation of pedicle screw fixation combined with kyphoplasty were included in this study.According to the follow-up results,such as the operation time,blood loss,postoperative drainage,hospitalization,ambulatory re-covery,kyphosis Cobb’s angle,visual analogue scale(VAS),Oswesay disability index(ODI),height restoration of the vertebral and complications were assessed.Results Patients were followed up for 22 to 28 months,mean 25 months;the operation time 150 to 190 min,mean(150±20)min;blood loss 400 to 550 mL,mean(450±30)mL;postoperative drainage 150 to 200 mL,mean(180±20)mL;hospitalization 10 to 15 days,mean(11.5±2.5)days;ambulatory re-covery 5 to 7 days,mean (4.5±1.5)days.Compared with pre-operation,significant differences (P<0.05) were found in kyphosis Cobb’s angle,visual analogue scale(VAS),oswesay disability index(ODI) and height restoration of the vertebral after post-operation.One case appeared adjacent vertebral fractures at follow up.There were no complications such as fixation loosen and broken.Conclusion Bone cement augmentation of pedicle screw fixation combined with kyphoplasty for stage Ⅲ Kummell Disease,can effectively restore spinal sagittal alignment,avoid vertebral collapse,secondary nerve injury and long-term bed-ridden complications,improve quality of life.