Platelet Rich Plasma Combined with MIPPO Technique in Treatment of Tibial Closed Fracture
1.Department of Trauma Surgery,Weihai Central Hospital Affiliated to Qingdao University
2.Department of Anesthesia,Wendeng Orthopedic Hospital of Shandong Province
3.Department of Orthopaedics,Weihai Central Hospital Affiliated to Qingdao University
Objective To investigate the effect of minimally invasive percutaneous plate osteosynthesis (MIPPO) combined with plateletrich plasma(PRP) for tibial shaft closed fractures.Methods A total of 62 patients with freshly closed tibial shaft fractures admitted to Weihai Central Hospital affiliated to Qingdao University from January 2019 to May 2020 were selected.Patients were divided into control group and treatment group according to random number table method,with 31 cases in each group.The treatment group with minimally invasive percutaneous plate fixation MIPPO at the same time of fracture end applications of PRP treatment.The control group was treated with MIPPO alone without PRP.In the treatment group,there were 19 males and 12 females.The average age was (38.48±12.01)years,ranging from 19~60 years.In the control group,there were 21 males and 10 females.The average age was (39.77±12.31)years,ranging from 19~57 years.Operation time,intraoperative blood loss,fracture healing time,complete weightbearing time,complications,JohnerWruhs excellent and good rate 12 months after surgery were recorded and compared between the two groups.Results All patients were followed up for more than 12 months.The complete weight-bearing time,fracture healing time and incision healing in the treatment group were better than those in the control group,and the differences were statistically significant (P<0.05).The curative effect was evaluated by Johner-Wruhs criteria 12 months after surgery.In the treatment group,27 cases were excellent,2 cases were good,and 2 cases were medium,with an excellent and good rate of 93.55%.In the control group,19 cases were excellent,3 cases were good,5 cases were medium,and 4 cases were poor,with an excellent and good rate of 70.97%.The therapeutic effect of the treatment group was better than that of the control group,and the difference was statistically significant (P<0.05).All fractures healed in the treatment group,and no obvious complications occurred after operation.One case of superficial infection in control group was cured by dressing change.Delayed fracture of union was observed in 1 patients,and the fracture healed until 11 months after surgery.Conclusion PRP combined with MIPPO technique can significantly shorten fracture healing time,reduce delayed fracture healing,reduce postoperative complications,and improve the functional activity of the affected limb,without obvious complications,which has clinical application value.
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