血栓弹力图及常规凝血功能与多发伤患者创伤严重程度的研究

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Abstract Objective To explore the clinical relationship between thromboelastogram，routine coagulation function and severity of trauma in patients with multiple trauma. Methods 126 patients with multiple injuries were selected from the Emergency Department of the Affiliated Hospital of Shanxi Medical University from April to November，2018.126 patients were divided into light group，medium group and heavy group according to Kampala trauma score at admission.TEG and routine coagulation tests were performed within 12 hours after injury.Another 30 healthy people in the same period were selected as control group to observe the differences of the experimental parameters of the four groups.The correlation between the parameters of the two methods was also analyzed.Results There were significant differences in fibrinogen，D-dimer and platelet counts between the four groups in routine coagulation tests.There was only significant difference in MA value between the four groups in TEG indexes.The correlation analysis between TEG parameters and routine coagulation indexes showed that R value was positively correlated with prothrombin time and activated partial thromboplastin time.K value was positively correlated with APTT and thrombin time，negatively correlated with Fib and PLT；alpha angle was positively correlated with Fib，D-dimer and PLT，negatively correlated with PT，APTT and TT；MA value was positively correlated with Fib and PLT，and negatively correlated with PT.Conclusion Early coagulation dysfunction in patients with multiple trauma of different degrees is diverse.Combined application of TEG and routine coagulation examination can comprehensively evaluate early coagulation dysfunction in patients with multiple trauma.

Key words： thrombelastography coagulation dysfunction multiple trauma severity of traum kampala trauma score

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	Huang Jing 1
	Yan Xinming 2*

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Huang Jing 1,Yan Xinming 2*. Study on Thromboelastography and Routine Coagulation Function and Severity of Trauma in Patients with Multiple Trauma[J]. sygkzz, 2019, 25(9): 804-829.

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http://www.sygkzz.com/EN/ OR http://www.sygkzz.com/EN/Y2019/V25/I9/804

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