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Abstract Objective To observe the application and long-term efficacy of autologous fibula graft in the treatment of pathological bone defect.Methods From May 2008 to July 2015，23 patients with pathological bone defect were treated.There were 14 males and 9 females，aged 0.5～72 years old，with an average of 22 years old.7 patients were treated with vascularized fibula graft and 16 patiemts without vascular graft.5 patients with iliac bone graft；2 patients with allograft bone transplantation；1 patients with iliac bone and artificial bone graft.Results 20 patients were followed up for 5～84 months (mean 24.7 months).X-ray examination showed that 17 graft survived and restored limb function.Bone healing time was 3～39 months.There were 3 patients with bone graft not survived.Conclusion Autologous fibular grafting is an ideal treatment for repairing pathological bone defects.
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