人工真皮与游离植皮修复指腹皮肤软组织缺损的比较研究

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Abstract Objective To compare the clinical effects of artificial dermis and free skin grafting in repairing skin and soft tissue defects of finger pulp.Methods A retrospective analysis was conducted on 115 patients with skin and soft tissue defects of finger pulp surgically managed between June 2018 and June 2020.Of the 115 patients，63 patients were treated with free skin grafting (the free skin grafting group)，while the remaining 52 patients treated with artificial dermis (the artificial dermis group).In the free skin graft group，there were 56 males and 7 females，with an average age of (45.56±7.57)years old.There were 47 males and 5 females in the artificial skin grafting group，with an average age of (48.85±6.26)years old.In the free skin grafting group，autologous medium thickness skin graft was used in the first stage after debridement，while the artificial dermis group was covered with artificial dermis.Both groups were set pressure bandaged after operation.The pressure package was removed 1 week after operation and the dressing was changed every other day.The graft survival rate，operation times，operation time，hospital stay and complete wound healing time were compared between the two groups.The sensory grade of finger abdomen and two-point discrimination were evaluated by international standards.The total active range of motion(TAM) system was used to evaluate the recovery of hand function in the two groups.Results There was no significant difference between the two groups in the graft survival rate，the number of operations and the hospital stay (P＞0.05).The operation time of free skin grafting group was longer than that of artificial dermis group (P＜0.05).The hospitalization cost and the wound complete healing time in the free skin grafting group were less than those in the artificial dermis group (P＜0.05).There was no significant difference between the two groups in the S3+ sensation rate，the two-point discrimination and the TAM score (P＞0.05).Conclusion The operation of repairing the skin and soft tissue defect of finger pulp with artificial dermis is simpler，less trauma and good clinical effect，but it increases the treatment time and hospitalization cost.

Key words： hand trauma finger pulp skin and soft tissue defect artificial dermis free skin grafting clinical effect

Corresponding Authors: Sun Zhongyang

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	Wang Chunshu
	Zhang Pengfei
	Wang Liang
	Xue Shihui
	Du Kang
	Wang Jianling
	Sun Zhongyang

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Wang Chunshu,Zhang Pengfei,Wang Liang, et al. Comparative Study of Artificial Dermis and Free Skin Grafting in Repairing Skin and Soft Tissue Defects of Finger Pulp[J]. sygkzz, 2022, 28(09): 778-.

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http://www.sygkzz.com/EN/ OR http://www.sygkzz.com/EN/Y2022/V28/I09/778

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