骨骼肌质量与老年退行性腰椎管狭窄患者椎管狭窄程度的相关性分析

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Abstract Objective To investigate the correlation between skeletal muscle mass and spinal stenosis degree in elderly patients with degenerative lumbar spinal stenosis(DLSS).Methods From June 2019 to October 2021，80 elderly patients with degenerative lumbar spinal stenosis(DLSS group) and 45 physical examination volunteers(control group)were selected.Absolute claudication distance(ACD) was measured to evaluate the degree of DLSS spinal stenosis. According to the degree of DLSS spinal stenosis，DLSS patients were divided into mild group(grade 5~6，22 cases)，moderate group(grade 3~4，41 cases)and severe group(grade 1~2，17 cases)，and were divided into sarcopenia group(23 cases)and no sarcopenia group(57 cases) according to whether or not combined with sarcopenia.Skeletal muscle mass of the whole body and limbs were measured by dual-energy X-ray absorptiometry，and the relative skeletal muscle index(RSMI) was calculated.The total cross-sectional area(TCSA) and total fatless cross-sectional area(TFCSA) of multifidus were measured by MRI，and the TCSA/TFCSA ratio was calculated.The relation between all skeletal muscle mass，limb skeletal muscle mass，RSMI and TCSA，TFCSA，TFCSA/ TCSA ratio and DLSS spinal stenosis were analyzed.Results The skeletal muscle mass of upper limb，lower limb，whole body，RSMI，TFCSA and TFCSA/TCSA ratio in DLSS group were lower than those in control group(P＜0.05).The skeletal muscle mass of upper limb，lower limb，whole body，RSMI，TFCSA and TFCSA/TCSA ratios in sarcopenia group were lower than those in no sarcopenia group(P＜0.05).The skeletal muscle mass of upper limb，lower limb，whole body，RSMI，TFCSA and TFCSA/TCSA ratios in severe group were lower than those in moderate group and mild group(P＜0.05)，and those in moderate group were lower than those in mild group(P＜0.05).In DLSS group，skeletal muscle mass of upper limb，lower limb，whole body and RSMI were positively correlated with TFCSA and TFCSA/TCSA ratio(P＜0.05)，but negatively correlated with spinal stenosis grade(P＜0.05).Conclusion Skeletal muscle mass in extremities and whole body is correlated with lumbar multifidus atrophy and spinal stenosis in elderly DLSS patients.

Key words： skeletal muscle mass sarcopenia degenerative lumbar spinal stenosis

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	You Lipan
	Wei Bo *

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You Lipan,Wei Bo *. Correlation Analysis Of Skeletal Muscle Mass And Spinal Stenosis-Degree In Elderly Patients With Degenerative Lumbar Spinal Stenosis[J]. sygkzz, 2022, 28(5): 390-411.

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http://www.sygkzz.com/EN/ OR http://www.sygkzz.com/EN/Y2022/V28/I5/390

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