人类免疫缺陷病毒阳性患者股骨头缺血性坏死的临床特点浅析

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Abstract Objective To investigate the clinical characteristics and risk factors of femur head necrosis in human immunodeficiency virus(HIV)positive patients.Methods 81 HIV-positive patients with femoral head necrosis admitted to our hospital from October 2015 to October 2019 were selected as the observation group，and 81 non-HIV-positive patients with femoral head necrosis corresponding to gender and age at the same period were selected as the control group.The clinical characteristics of the two groups were compared.Results There was no statistical difference(P＞0.05)between observation group and control group in career，location，ARCO stage，hip pain visual analog scale(visual analogue scale，VAS)score，hip flexion and Harris hip joint function score，no differences were found between the two groups in hypertension，cardiovascular disease，diabetes，hyperlipidemia and other complications，serum albumin were found no statistical difference between the two groups(P＞0.05)，The ratio of alcohol-induced femoral head necrosis in the observation group(2.50%)was significantly lower than that in the control group(43.21%)，and the difference was statistically significant(P<0.05).The hemoglobin level and BMI of the observation group were significantly lower than that in the control group(P<0.05).The count of CD4+T cells in peripheral blood of patients in the observation group was generally low，among which 32 cases(39.51%)had CD4+T cells <200 / μL.Conclusion There is no significant difference in the incidence and severity of non-traumatic femoral head necrosis in HIVpositive patients compared with the normal population.Among HIV-positive patients，the ratio of alcohol-induced non-traumatic femoral head necrosis is significantly lower than that of the control group.CD4+T cell count in peripheral blood of such patients is generally low，so certain attention should be paid during surgical treatment.

Key words： human immunodeficiency virus necrosis of femoral head the cause

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