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Abstract Objective To explore the risk factors of deep venous thromhosis(DVT)after spinal surgery，analyze and find out related high-risk factors，and provide evidence for preventing and reducing the formation of deep venous thromhosis after spinal surgery.Methods The postoperative clinical data of 480 patients with spinal diseases admitted to the Orthopedic Center of the First Affiliated Hospital of Xinjiang Medical University from June 2016 to June 2020 were retrospectively analyzed，According to the results of ultrasound diagnosis of lower extremity veins within 1 week after operation，patients were divided into DVT group(30 cases)and non-DVT group(450 cases).Wecompared the age，gender，body mass index(BMI)，history of smoking，drinking history，tumor，hypertension，hyperlipidemia，and diabetes，preoperative D-dimer，and spinal cord Injury，the use of anticoagulants，the presence or absence of intraoperative blood transfusion，vertebral body segments，whether intraoperative nerve root decompression，intraoperative blood loss，surgical duration and postoperative time to the ground and other related factors.AndLogistic regression model Multivariate analysis was used to analyze the risk factors of postoperative DVT.Results Univariate analysis showed that there was difference between the two groups of patients in terms of age composition，BMI，smoking history，diabetes，preoperative D-dimer abnormalities，whether they were combined with spinal cord injury，whether they were taking anticoagulants，whether they received blood transfusions，vertebral body segments，and whether they received nerve root decompression.There were significant differences in factors such as root decompression，intraoperative blood loss ≥500 mL，operation time，and postoperative time to ground(P<0.05).Logistic regression model showed that age，preoperative D-dimer abnormality，intraoperative blood transfusion，multi-segment vertebral body，intraoperative nerve root decompression，postoperative time to ground ≥5 days were statistically associated with the formation of DVT after spinal surgery(P<0.05).Conclusion Age ≥60 years old，preoperative D-dimer abnormality，intraoperative blood transfusion，multi-segment vertebral body，intraoperative nerve root decompression，and postoperative landing time ≥5 days are high risk factors for the formation of DVT after spinal disease.Patients with spinal diseases with this high-risk factor should closely prevent the occurrence of DVT after spinal surgery.
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