富血小板血浆治疗膝关节髌骨软化症的短期疗效观察

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Abstract Objective To observe the clinical efficacy of Platelet-rich plasma(PRP)in the treatment of chondromalacia patellae of knee joint.Methods 60 patients with patellar malacia disease were randomly divided into two groups，30 patients in each group.The experimental group (group A) was injected with autologous PRP in the joint cavity，while the control group (group B) was injected with cross-linked sodium hyaluronate in the joint cavity.Changes in visual analogue scale (VAS) and Western Ontario and McMaster Universities Arthritis Index(WOMAC) were observed 1 month，3 months，6 months，and 1 year after treatment. Results After 1 month of treatment，VAS scores in group A and B were significantly lower than those before treatment (P<0.05).VAS and WOMAC scores of group A and B were different after 1 month and 3 months of treatment，but there was no statistical significance.VAS and WOMAC scores after 6 months and 1 year of treatment were significantly better in group A than in group B，with statistically significant differences (P<0.05).During the follow-up，VAS and WOMAC scores in group A continued to decrease，while VAS score and WOMAC scores of group B increased 6 months after treatment.Conclusion Platelet rich plasma therapy can significantly improve the pain and joint function of patellomalacia，and has a stable short-term effect.

Key words： platelet rich plasma crosslinked sodium hyaluronate chondromalacia patellae curative effect

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http://www.sygkzz.com/EN/ OR http://www.sygkzz.com/EN/Y2020/V26/I12/1135

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