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Abstract Objective To investigate the stress distribution of the femoral stem with 3D printing trabecular structure by establishing solid structure and trabecular structure femoral stem prosthesis and using finite element simulation.Methods By comparing the three-dimensional models of solid structure prosthesis and 3D printing trabecular structure femoral stem prosthesis，a finite element model was established to simulate the standing state of prosthesis with different structural designs after implantation，and the biomechanical properties of the two designs were compared.Results The results showed that the peak stress in the finite element model appeared in the area of 3D printing trabecular structure.When standing on one foot，the peak stress of femoral stem with 3D printing trabecular structure was 8.6 MPa.The peak stress of the femoral stem with 3D printing trabecular structure was 3.9 MPa when the feet were standing.Conclusion Compared with the solid structure of femoral stem prosthesis，the stress distribution of 3D printing trabecular bone structure is significantly optimized，and the maximum stress value is significantly reduced；therefore，the superior mechanical bearing performance of 3D printing bone trabecular structure reduces the stress shielding effect of femoral stem，which is more conducive to bone growth around the prosthesis，thus avoiding prosthesis loosening and providing safety guarantee for patients' rehabilitation.
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