自体腘绳肌腱修复兔巨大肩袖缺损的实验研究

Abstract
Figure/Table
References (0)
Related Citation (15)

Download: PDF (1958 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the early healing outcomes of tendons and bones in huge rotator cuff defect of rabbits treated with autologous hamstring tendon. Methods Forty male New Zealand white rabbits were randomly divided into three groups：normal group(n＝8)，model group(n＝8)and experimental group(n＝24).The normal group was rfed in the same manner but was not treated.In the model group，a 1.5 cm×1.0 cm rotator cuff defect was made by cutting from the greater tuberosity of humeral head of both forelegs of the rabbits and the skin was directly closed without suture repair.In the experimental group，the huge rotator cuff defect was further repaired by suturing with autologous hamstring tendon on the basis of the model group.8 white rabbits were sacrificed at 8，16，and 24 weeks after surgery in the experimental group and specimens of rotator cuff in both forelegs were collected，which were processed for histomorphological analysis and biomechanical research tests.Results Histomorphological analysis showed that collagen fibers increased significantly at the tendon-bone interface at 24 weeks after the operation in the experimental group.Healing components like Sharpey fibers，fibrochondrocytes，and fibrocartilage were found at the tendon-bone junction of the cut.Biomechanical analysis showed that the maximum load of tendons in the experimental group continued to increase with time(comparison between time points，P＜0.05)，and strong mechanical strength could be obtained after 24 weeks.Conclusion The application of autologous hamstring tendon to repair huge rotator cuff defects can lead to satisfactory tendon bone healing outcomes in rabbits.

Key words： irreparable rotator cuff tear rotator cuff repair hamstring tendon autografts biomechanical analysis

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

http://www.sygkzz.com/EN/ OR http://www.sygkzz.com/EN/Y2020/V26/I2/132

［1］Greenspoon JA，Petri M，Millett PJ.Arthroscopic knotless，double-row，extended linked repair for massive rotator cuff tears［J］.Arthrosc Tech，2016，5(1)：e127-e132.
［2］Allert JW，Sellers TR，Simon P，et al.Massive rotator cuff tears in patients older than sixty-five：Indications for cuff repair versus reverse total shoulder arthroplasty［J］.Am J Orthop(Belle Mead NJ)，2018，47(12)：101-105.
［3］李小飞，谢文瑾，盛路新.老年退变性肩袖损伤的肩关节镜治疗［J］.实用骨科杂志，2016，22(2)：107-110.
［4］Liu X，Ning AY，Chang NC，et al.Investigating the cellular origin of rotator cuff muscle fatty infiltration and fibrosis after injury［J］.Muscles J，2016，6(1)：6-15.
［5］刘岳，郭洪敏，聂志奎，等.不同方法治疗慢性肩袖钙化性肌腱炎的疗效对比［J］.实用骨科杂志，2016，22(4)：352-354.
［6］Barth J，Andrieu K，Fotiadis E，et al.Critical period and risk factors for retear following arthroscopic repair of the rotator cuff［J］.Knee Surg Sports Traumatol Arthrosc，2016，25(7)：1-9.
［7］Jeong HJ，Rhee SM，Oh JH.Postoperative new-onset pseudoparalysis：a retrospective analysis of 430 consecutive arthroscopic repairs for large to massive rotator cuff tears［J］.Am J Sports Med，2018，46(7)：1701-1710.
［8］王微，李剑，李红川，等.关节镜下穿肌腱技术治疗关节侧部分肩袖损伤［J］.实用骨科杂志，2017，23(2)：97-99.
［9］Sano H，Kumagai J，Sawai T.Experimental fascial autografting for the supraspinatus tendon defect：remodeling process of the grafted fascia and the insertion into bone［J］.J Shoulder Elbow Surg，2002，11(2)：166-173.
［10］Moore DR，Cain EL，Schwartz ML，et al.Allograft reconstruction for massive，irreparable rotator cuff tears［J］.Am J Sports Med，2006，34(3)：392-396.
［11］Thangarajah T，Pendegrass CJ，Shahbazi S，et al.Augmentation of rotator cuff repair with soft tissue scaffolds［J］.Orthop J Sports Med，2015，3(6)：232-235.
［12］Narvani AA，Consigliere P，Polyzois I，et al."Owl" technique for all-arthroscopic augmentation of a massive or large rotator cuff tear with extracellular matrix graft［J］.Arthrosc Tech，2016，5(4)：e717-e724.
［13］史福东，冯世庆，左金增，等.关节镜下自体腓骨长肌腱和腘绳肌腱重建前交叉韧带的对比［J］.中华实验外科杂志，2014，31(11)：2531-2533.
［14］张磊，陈百成，马世云，等.关节镜下自体腘绳肌腱和同种异体胫前肌腱解剖止点中点单束重建前交叉韧带的比较研究［J］.中国内镜杂志，2015，21(12)：1290-1294.
［15］孙磊，宁廷民，田敏，等.关节镜下自体四股腘绳肌腱重建膝前交叉韧带［J］.中华创伤杂志，2005，21(5)：336-340.
［16］刘玉杰，李海峰，王俊良，等.腘绳肌腱移植股骨与胫骨端可吸收横钉固定法重建前交叉韧带［J］.中华医学杂志，2009，89(29)：2034-2037.
［17］翟文亮，练克俭，宋光虎.腘绳肌腱重建前交叉韧带移植肌腱的固定［J］.中国组织工程研究与临床康复，2007，11(16)：3140-3143.
［18］Sener M，Altay MA，Baki C，et al.The comparison of patellar tendon-bone autografting and free flexor-tendon autografting in infraspinatus defect of the shoulder：biomechanical and histological evaluation in a sheep model［J］.Knee Surg Sports Traumatol Arthrosc，2004，12(3)：235-240.
［19］王泽锦，黄炯锋，黄炳生，等.关节镜下4束自体腘绳肌腱与异体胫前肌腱移植重建前交叉韧带的临床对比研究［J］.中国骨科临床与基础研究杂志，2015，1(1)：17-23.
［20］孙鲁宁，赵金忠，沈计荣，等.关节镜下保留残存纤维结合七股自体腘绳肌腱单束重建后交叉韧带［J］.中国骨与关节损伤杂志，2012，27(2)：115-117.

[1]	. [J]. sygkzz, 2021, 27(4): 359-362.