Abstract:Objective To detect the clinical results of intraarticular cocktail application in TKA.Methods 102 patients underwent total knee arthroplasty at Beijing TsinghuaChanggung Hospital.52 patients in intraarticular injection group,11 were male and 41 were female,with an average age of (68.2±6.4)years old.50 patients in tissue injection group,including 16 males and 34 females,with an average age of (63.8±12.5)years old.The difference of visual analogue scale (VAS),hemoglobin (Hb) and Albumin(Alb) between two groupswere analyzed.Results There was no difference in Hb and Alb between two groups,otherwise,the VAS of 24 hours postoperative in intraarticular injection group was significant lower than tissue injection group.Conclusion Although intraarticular cocktail injection can not give a significantly advantage to traditional method,but it can obviously reduce pain in long.In addition,intraarticular cocktail injection has many advantages such as simple injection and saving operation time compared with tissue injection after TKA.
[1]Rhee SJ,Hong SM,Suh JT.High-flexion total knee arthroplastyusing nexgen LPS-Flex system:minimum 5-year follow-up results[J].Knee Surg Relat Res,2015,27(3):156-162.
[2]余振阳,蔡谞,谷旺.“鸡尾酒”配方药物膝关节周围注射在全膝关节置换术围手术期镇痛中的应用[J].中医正骨,2016,28(12):38-41.
[3]Badalamente MA,Cherney SB.Periosteal and vascular nnervation of the human patella in degenerative joint disease[J].Semin Arthritis Rheum,1989,18(4 Suppl 2):61-66.
[4]Moghtadaei M,Farahini H,Faiz SH,et al.Pain management for total knee arthroplasty:single-injection femoral nerve block versus local infiltration analgesia[J].Iran Red Crescent Med J,2014,16(1):e13247.
[5]Skolnik A,Gan TJ.New formulations of bupivacaine for the treatment of postoperative pain:liposomal bupivacaine and Saber-Bupivacaine[J].Expert Opin Pharmacother,2014,15(11):1535-1542.
[6]Nakagawa S,Arai Y,Inoue H,et al.Comparative effects of periarticular multimodal drug injection and single-shot femoral nerve block on pain following total knee arthroplasty and factors influencing their effectiveness[J].Knee Surg Relat Res,2016,28(3):233-238.
[7]杨礼庆,马超,杜帅,人工全膝关节置换术围手术期疼痛管理现状[J].中国矫形外科杂志,2017,25(3):247-250.
[8]时利军,高福强,孙伟,等.鸡尾酒疗法减少全膝关节置换后隐性失血[J].中国组织工程研究,2017,21(3):329-334.
[9]Gibbs DM,Green TP,Esler CN.The local infiltration of analgesia following total knee replacement:a review of current literature[J].J Bone Joint Surg(Br),2012,94(9):1154-1159.
[10]Andersen LO,Kehlet H.Analgesic efficacy of local infiltration analgesia in hip and knee arthroplasty:a systematic review[J].Br J Anaesth,2014,113(3):360-374.
[11]Fan L,Zhu C,Zan P,et al.Thecomparison of local infiltration analgesia with peripheral nerve block following total knee arthroplasty (TKA):asystematic review with meta-analysis[J].J Arthroplasty,2015,30(9):1664-1671.
[12]Lombardi AV,Berend KR,Mallory TH,et al.Soft tissue and intra-articular injection of bupivacaine,epinephrine,and morphine has a beneficial effect after total knee arthroplasty[J].Clin Orthop Relat Res,2004(428):125-130.